References

  1. Werbach MR. Nutritional Strategies for Treating Chronic Fatigue Syndrome. Altern Med Rev 2000;5(2):93-108.

  2. National Institutes of Health (NIH). Magnesium: Fact Sheet for Health Professionals. [Online] 2013 Nov 4 [cited 2017 August 15]. Available from: URL: http://ads.ad.nih.gov/factsheets/Magnesium-HealthProfessional/.

  3. de Baaij J HF, Hoenderop JGJ, Bindels RJM. Magnesium in Man: Implications for Health and Disease. Physiol Rev 2015;95:1-46.

  4. Huskisson E, Maggini S, Ruf M. The Influence of Micronutrients on Cognitive Function and Performance. J Int Med Res 2007;35:1 -19.

  5. Nielsen FH, Lukaski HC. Update on the relationship between magnesium and exercise. Magn Res 2006;19(3):180-189.

  6. Nica AS, Caramoci A, Vasilescu M, Lonescu AM, Paduraru D, Mazilu V. Magnesium supplementation in top ath letes — effects and recommendations. Medicina Sportiva 2015;XI(1):2482-2494.

  7. Lukaski HC, Nielsen FH. Dietary Magnesium Depletion Affects Metabolic Responses during Submaximal Exercise in Post-menopausal Women. J Nutri 2002;132:93 0-935.

  8. Outhoff K. Magnesium: effects on physical and mental performance. Prof Ners Today 2016;20(2):7-9.

  9. Nica AS, Caramoci A, Vasilescu M, lonescu AM, Paduraru D, Mazilu V. Magnesium supplementation in top athletes - effects and recommendations. Medicina Sportiva 2015;XI(1):2482-2494.

  10. Lukaski HC, Nielsen FH. Dietary Magnesium Depletion Affects Metabolic Responses during Submaximal Exercise in Postmenopausal Women. J Nutri 2002;132:93 0-935.

  11. Royal Society of Chemistry. Periodic Table: Magnesium. [online] [cited 2018 Sep 11]. Available from: URL: http:/Awrw.rsc.org/periodic-table/eIemenV12/

  12. Costello R, Wallace TC, Rosanoff A. Magnesium. Adv Nutr 2016;7:199-201.

  13. Swaminathan R. Magnesium Metabolism and its Disorders. Clin Biochem Rev 2003;24:47-66.

  14. Panahi Y, Mojtahedzadeh M, Jahafi A, Reza Ghainis M, Al:dollah M, Sharitzadeh M, et al. Review anicle: The Role of Magnesium Sulfate in the Intensive Care Unit. EXCLI Journal 2017;16:464-482.

  15. European Food Safety Authority (EFSA) Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to magnesium and "homonal health' (ID 243), reduction of tiredness and fatigue (ID 244), contribution to normal psychological functions (ID 245, 246), maintenance of normal blood glucose concentrations (ID 342), maintenance of normal blood pressure (ID 344, 366, 379), protection of DNA, proteins and lipids from oxidative damage (ID 351), maintenance of the nomal function of the immune system (ID 352), maintenance of nornal blood pressure during pregnancy (ID 367), resistance to mental stress (ID 375, 381), reduction of gastric acid levels (ID 376), maintenance of nornal fat metabolism (ID 378) and maintenance of normal nuscle contraction (ID 380, ID 3083) pursuant to Article 13(1) of Regulation (EC) No 1924/20061. EFSA Journal 2010;8(10):1907.

  16. Cass H. A Practical Guide to Avoiding Drug-Induced Nutrient Depletion. Nutr Rev Arch. [online] 2016 Dec 11[cited 2018 Aug 7]. Available from: URL: http://nutritionreview.org/2013/04/practical-guide-avoiding-druginduced-nutrient -depletion/.

  17. Abbasi R, Kimiagar M, Sadeghniiat k, shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci 2012;17(12):1161-1169.

  18. Zhang y, Xun P, Wang R, Mao L, He K. Can Magnesium Enhance Exercise Performance? Nutr 2017;9:946.

  19. Davis CP. Fatigue. [Online] 2017 Nov 9 [cited 2018 Sep 11]. Available Jrom: URL: https://www.emedicinehealth.com/fatigue/anicle em.htm.

  20. Rosenthal TC, Majeroni BA, Pretorius R. Fatigue: An Overview. Am Fam Physician 2008; 78(10):1173-1179.

  21. Wishart K. Increased Micronutrient Requirements during Physiologically Demanding Situations: Iteview of the Current Evidence. Vitam Miner 2017;6(2):3.

  22. North Dakota State University (NDSU). How does the brain produce movement? Chapter 10:354-397. |onIine] [cited 2018 Sep 11. Available from: URL: httgs://www.ndsu.edu/faculty/pavek/Psych486 686/ch.

  23. Burton DA, Stokes K, Hall GM. Physiological effects of exercise. Crit Care Pain 2004;4(6):185-188.

  24. Morici G, Gruttad‘Auria CI, Baiamonte P, Mazzuca E, Castrogiovanni A, Bonsignore MR. Endurance training: is it bad for you+ Breathe 2016;12:140-147.

  25. Aurélio M, Peluso M, Guerra de Andrade LHS. Physical activity and mental health: the association beMeen exercise and mood. Clinics 2005;60(1):61-70.

  26. American Dietetic Association. Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and Athletic Performance. J Am Diet Assoc 2009;109:509-527.

  27. Lukaski HC. Magnesium, Zinc, and Chromium Nutrition and Athletic Perfomance. Can J Appl Physiol 2001;26(Suppl.):513-522.

  28. Kass LS, Poeira F. The effect of acute vs chronic magnesium supplementation on exercise and recovery on resistance exercise, blood pressure and total peripheral resistance on normotensive aduls. J Int Soc Sports Nutr 2015;12:19.

  29. Brilla LR. Magnesium Influence on Stress and Immune Funnion in Exercise. J Spans Med Doping Stud 2012;2(3):1000111.

  30. Lukaski HC. Magnesium, zinc, and chromium nutriture and physical activity. Am J Clin Nutr 2000;72(suppl):585S-593S.

  31. Cakmak I. Magnesium in crop production, food quality and human health. Plant soil 2013;368:1-4.

  32. Guo W, Nazim H, Liang Z, Yang D. Magnesium deficient in plants: An urgent problem. The Crop I 2016;4:83 -91.

  33. Davis DR. Declining Fruit and Vegetable Nutrient Composition: What Is the Evidence? Hort Sci 2009;44(1):15-19.

  34. Haivard Med ical School. Foods that fight fatigue. [online] |cited 2018 Oct 10]. Available from: URL: https://www.health.harvard.edu/healthbeat/foods- that-fight-fatigue.

For full prescribing information refer to the package insert.

[S0] Slow-Mag® Tablets. Each enteric-coated tablet contains magnesium chloride 535 mg, providing 64 mg magnesium (elemental). SA Reg. No.: H/24/89. BOT Reg. No.: S3 B9306530

Slow-Mag® Capsules *. Each capsule contains magnesium lysinate glycinate chelate 450 mg, providing 45 mg magnesium (elemental).

Slow-Mag® Fizzies *. Each effervescent tablet contains magnesium carbonate 707,980 mg, providing 172 mg magnesium (elemental) and ascorbic acid 165,100 mg, providing 150 mg vitamin C.

*Complementary medicine: Health supplement. This unregistered medicine has not been evaluated by SAHPRA for its quality, safety or intended use.


Applicant: P&G South African Trading (Pty) Ltd.
Reg. No.: 1989/004241/07.12th floor,
Alice Lane Towers, 15 Alice Lane, Sandton, South Africa, 2196.

Report adverse events to PHCQueriesAfrica.im@pg.com.
{MAT-ZA-OTHER-20-000028 and 4/21/2020}